Article
Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues.
The Journal of general virology - 1 Sept 2014
Maluquer de Motes Carlos, Schiffner Torben, Sumner Rebecca P, Smith Geoffrey L
Abstract excerpt
Ubiquitylation is a covalent post-translational modification that regulates protein stability and is involved in many biological functions. Proteins may be modified with mono-ubiquitin or ubiquitin chains. Viruses have evolved multiple mechanisms to perturb the cell ubiquitin system and manipulate it to their own benefit. Here, we report ubiquitylation of vaccinia virus (VACV) protein N1. N1 is an inhibitor of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
