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Article

The mechanistic role of DNA methylation in myeloid leukemogenesis.

Leukemia - 1 Sept 2014

Jasielec J, Saloura V, Godley L A

Abstract excerpt

The importance of epigenetic aberrations in the pathogenesis of leukemias has been revealed by recurrent gene mutations that highlight epigenetic pathways as well as by the clinical success of therapies like 5-azacytidine and decitabine that work through epigenetic mechanisms. However, precise mechanisms of how gene mutations lead to leukemias and how epigenetic therapies induce clinical remissions are elusive....

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Identifiers

PMID: 24913729
DOI: 10.1038/leu.2014.163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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