Article
Maintenance of the contractile phenotype in corpus cavernosum smooth muscle cells by Myocardin gene therapy ameliorates erectile dysfunction in bilateral cavernous nerve injury rats.
Andrology - 1 Jul 2017
Zhang H-B, Wang Z-Q, Chen F-Z, Ding W, Liu W-B, Chen Z-R, He S-H, Wei A-Y
Abstract excerpt
The pathophysiology of erectile dysfunction post radical prostatectomy is not clearly clarified, and the low efficacy of traditional PDE5i treatment remains a major complaint in contemporary practice. This study aimed to demonstrate phenotypic modulation in bilateral cavernous nerve injury (BCNI) rats within 7 days, and subsequently validate gene therapy with Myocardin (Mycod) by maintaining a contractile...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.