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Article

Phenotypic modulation of vascular smooth muscle cells in the corpus spongiosum surrounding the urethral plate in hypospadias.

Andrologia - 1 Nov 2022

Huang Jiayao, Huang Yichen, Shi Xiujuan, Lyu Yiqing, Wu Min, Chen Yan, Zhou Lijun, Yu Huan, Xie Hua, Chen Fang

Abstract excerpt

Hypospadias is an abnormal ventral development of the penis caused by incomplete virilization of the male genital tubercle. This study investigated the phenotypic modulation of vascular smooth muscle cells (VSMCs) in the corpus spongiosum surrounding the urethral plate in hypospadias. The urethral corpus spongiosum tissue was collected for HE, Masson and α-SMA immunohistochemical staining. Spongiosum VSMCs were...

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PMID: 35866316
DOI: 10.1111/and.14540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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