The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.

doi:10.1038/srep05208

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.

Scientific reports - 6 Jun 2014

Wang Wei, Lou Jiao, Zhong Rong, Qi Yan-qi, Shen Na, Lu Xu-zai, Wang Yu-jia, Zhang Qing, Zou Li, Duan Jia-yu, Ke Jun-tao, Miao Xiao-ping, Gong Fang-qi

Abstract excerpt

Ca(2+)/nuclear factor of activated T-cells (Ca(2+)/NFAT) signaling pathway may play a crucial role in Kawasaki disease (KD). We investigated 16 genetic variants, selected by bioinformatics analyses or previous studies, in 7 key genes involved in this pathway in a Chinese population. We observed a significantly or marginally increased KD risk associated with rs2720378 GC + CC genotypes (OR = 1.39, 95% CI =...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Caspase 3

Share to Mucocutaneous Lymph Node Syndrome

Share to NFATC Transcription Factors

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Risk Factors

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 24903211
DOI: 10.1038/srep05208
PMCID: PMC4047536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.PMID 24903211Read ↗

Molecular genetics of Kawasaki disease.Semantic proximity Read ↗

Combined analysis of genome-wide-linked susceptibility loci to Kawasaki disease in Han Chinese.Semantic proximity Read ↗

Understanding the pathogenesis of Kawasaki disease by network and pathway analysis.Semantic proximity Read ↗

Variations in ORAI1 Gene Associated with Kawasaki Disease.Semantic proximity Read ↗

Systematic confirmation study of GWAS-identified genetic variants for Kawasaki disease in a Chinese population.Semantic proximity Read ↗

The Roles of Genetic Factors in Kawasaki Disease: A Systematic Review and Meta-analysis of Genetic Association Studies.Semantic proximity Read ↗

8p22-23-rs2254546 as a susceptibility locus for Kawasaki disease: a case-control study and a meta-analysis.Semantic proximity Read ↗

A genome-wide association analysis identifies NMNAT2 and HCP5 as susceptibility loci for Kawasaki disease.Semantic proximity Read ↗

A genome-wide association study identifies three new risk loci for Kawasaki disease.Semantic proximity Read ↗

Update of genetic susceptibility in patients with Kawasaki diseaseSemantic proximity Read ↗

Single-nucleotide polymorphism rs7251246 in ITPKC is associated with susceptibility and coronary artery lesions in Kawasaki disease.Semantic proximity Read ↗

A critical appraisal of the role of intracellular Ca2+-signaling pathways in Kawasaki disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.