Article
Understanding the pathogenesis of Kawasaki disease by network and pathway analysis.
Computational and mathematical methods in medicine - 1 Jan 2013
Lv Yu-wen, Wang Jing, Sun Ling, Zhang Jian-min, Cao Lei, Ding Yue-yue, Chen Ye, Dou Ji-juan, Huang Jie, Tang Yi-fei, Wu Wen-tao, Cui Wei-rong, Lv Hai-tao
Abstract excerpt
Kawasaki disease (KD) is a complex disease, leading to the damage of multisystems. The pathogen that triggers this sophisticated disease is still unknown since it was first reported in 1967. To increase our knowledge on the effects of genes in KD, we extracted statistically significant genes so far associated with this mysterious illness from candidate gene studies and genome-wide association studies. These genes...
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