Article
Combined analysis of genome-wide-linked susceptibility loci to Kawasaki disease in Han Chinese.
Human genetics - 1 Jun 2013
Yan Yuanlong, Ma Yongyi, Liu Yunqiang, Hu Hongde, Shen Ying, Zhang Sizhong, Ma Yongxing, Tao Dachang, Wu Qing, Peng Qian, Yang Yuan
Abstract excerpt
Kawasaki disease (KD) is a dominant cause of acquired heart disease in children due to frequent complicating coronary artery lesions (CALs). Genome-wide association study and linkage analysis have recently identified 6 susceptibility loci at genome-wide significance of P < 5.0 × 10(-8) in subjects of Japanese, Taiwanese and European. In present study, we analysed the variants of 6 single nucleotide polymorphisms...
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