Article
HIV-1 subtype A gag variability and epitope evolution.
PloS one - 1 Jan 2014
Abidi Syed Hani, Kalish Marcia L, Abbas Farhat, Rowland-Jones Sarah, Ali Syed
Abstract excerpt
OBJECTIVE: The aim of this study was to examine the course of time-dependent evolution of HIV-1 subtype A on a global level, especially with respect to the dynamics of immunogenic HIV gag epitopes. METHODS: We used a total of 1,893 HIV-1 subtype A gag sequences representing a timeline from 1985 through 2010, and 19 different countries in Africa, Europe and Asia. The phylogenetic relationship of subtype A gag and...
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