Article
Molecular evolution of human immunodeficiency virus type 1 subtype A in Senegal: 1988-1997.
Journal of human virology - 1 Jan 2000
Sankalé J L, Hamel D, Woolsey A, Traoré T, Dia T C, Guèye-Ndiaye A, Essex M, Mboup T, Kanki P
Abstract excerpt
OBJECTIVE: Few studies have been able to track the genetic diversity of HIV-1 viruses in human populations over time. We analyzed the molecular evolution of subtype A over a 10-year period, in a cohort of female sex workers with a known time of infection. STUDY DESIGN/METHODS: We amplified and sequenced the C2-V3 region of the surface envelope glycoprotein from 73 HIV-1-infected women, infected between 1987-1997....
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