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Article

Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma.

Oncology reports - 1 Aug 2014

Ko Josephine My, Zhang Peng, Law Simon, Fan Yanhui, Song You-Qiang, Zhao Xue Ke, Wong Elibe H W, Tang Sa, Song Xin, Lung Maria Li, Wang Li Dong

Abstract excerpt

Worldwide, the highest prevalence of esophageal cancer (EC) occurs in Northern China. High-density SNP arrays allow identification of identity-by-descent (IBD) segments in genomic DNAs representative of shared common ancestral regions. We utilized IBD approaches to map susceptibility loci associated with low-penetrance SNPs in high-risk Henan hereditary esophageal squamous cell carcinoma (ESCC) patients....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24890309
DOI: 10.3892/or.2014.3222

Genes

GPT2
PLCE1
SIAH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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