Article
GWAS follow-up study of esophageal squamous cell carcinoma identifies potential genetic loci associated with family history of upper gastrointestinal cancer.
Scientific reports - 5 Jul 2017
Song Xin, Li Wen-Qing, Hu Nan, Zhao Xue Ke, Wang Zhaoming, Hyland Paula L, Jiang Tao, Kong Guo Qiang, Su Hua, Wang Chaoyu, Wang Lemin, Sun Li, Fan Zong Min, Meng Hui, Zhang Tang Juan, Ji Ling Fen, Hu Shou Jia, Han Wei Li, Wu Min Jie, Zheng Peng Yuan, Lv Shuang, Li Xue Min, Zhou Fu You, Burdett Laurie, Ding Ti, Qiao You-Lin, Fan Jin-Hu, Han Xiao-You, Giffen Carol, Tucker Margaret A, Dawsey Sanford M, Freedman Neal D, Chanock Stephen J, Abnet Christian C, Taylor Philip R, Wang Li-Dong, Goldstein Alisa M
Abstract excerpt
Based on our initial genome-wide association study (GWAS) on esophageal squamous cell carcinoma (ESCC) in Han Chinese, we conducted a follow-up study to examine the single nucleotide polymorphisms (SNPs) associated with family history (FH) of upper gastrointestinal cancer (UGI) cancer in cases with ESCC. We evaluated the association between SNPs and FH of UGI cancer among ESCC cases in a stage-1 case-only...
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