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Article

Network analysis identifies protein clusters of functional importance in juvenile idiopathic arthritis.

Arthritis research & therapy - 8 May 2014

Stevens Adam, Meyer Stefan, Hanson Daniel, Clayton Peter, Donn Rachelle P

Abstract excerpt

INTRODUCTION: Our objective was to utilise network analysis to identify protein clusters of greatest potential functional relevance in the pathogenesis of oligoarticular and rheumatoid factor negative (RF-ve) polyarticular juvenile idiopathic arthritis (JIA). METHODS: JIA genetic association data were used to build an interactome network model in BioGRID 3.2.99. The top 10% of this protein:protein JIA Interactome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24886659
DOI: 10.1186/ar4559
PMCID: PMC4062926

Genes

KSR1
PTPN2
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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