Article
Genomic analysis of the emergence of 20th century epidemic dysentery.
BMC genomics - 10 May 2014
Rohmer Laurence, Jacobs Michael A, Brittnacher Mitchell J, Fong Christine, Hayden Hillary S, Hocquet Didier, Weiss Eli J, Radey Matthew, Germani Yves, Talukder Kaisar Ali, Hager Anthony J, Kemner John M, Sims-Day Elizabeth H, Matamouros Susana, Hager Kyle R, Miller Samuel I
Abstract excerpt
BACKGROUND: Shigella dysenteriae type 1 (Sd1) causes recurrent epidemics of dysentery associated with high mortality in many regions of the world. Sd1 infects humans at very low infectious doses (10 CFU), and treatment is complicated by the rapid emergence of antibiotic resistant Sd1 strains. Sd1 is only detected in the context of human infections, and the circumstances under which epidemics emerge and regress...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
