Article
Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.
Genome research - 1 Nov 2016
David Sophia, Rusniok Christophe, Mentasti Massimo, Gomez-Valero Laura, Harris Simon R, Lechat Pierre, Lees John, Ginevra Christophe, Glaser Philippe, Ma Laurence, Bouchier Christiane, Underwood Anthony, Jarraud Sophie, Harrison Timothy G, Parkhill Julian, Buchrieser Carmen
Abstract excerpt
Legionella pneumophila is an environmental bacterium and the leading cause of Legionnaires' disease. Just five sequence types (ST), from more than 2000 currently described, cause nearly half of disease cases in northwest Europe. Here, we report the sequence and analyses of 364 L. pneumophila genomes, including 337 from the five disease-associated STs and 27 representative of the species diversity. Phylogenetic...
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