Article
[Differentiated murine F9 teratocarcinoma cells are susceptible to apoptosis upon contact with substrate].
Tsitologiia - 1 Jan 2000
Lianguzova M S, Pospelov V A, Kisliakova T V
Abstract excerpt
Epithelial and endothelial cells are susceptible to a subset of apoptosis known as anoikis. This type of programmed cell death is activated upon disruption of cell-substrate contacts. Here we demonstrate that mouse F9 embryonal carcinoma cell line acquires susceptibility to anoikis upon retinoic acid-induced differentiation towards non-malignant pariental endoderm-like cells. F9 cells survival becomes dependent...
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