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Article

Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis.

Journal of cell science - 1 Sept 2000

Johnson V L, Ko S C, Holmstrom T H, Eriksson J E, Chow S C

Abstract excerpt

Nuclear morphological changes during apoptosis are very distinct and effector caspases have been implicated to play a central role in these processes. To investigate this in greater detail we examined the effect of blocking caspase activity and its activation on the nuclear morphological change in Jurkat T cells undergoing apoptosis after staurosporine treatment. In the presence of caspase inhibitors, like...

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Identifiers

PMID: 10934034
DOI: 10.1242/jcs.113.17.2941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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