Article
Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop.
BMC infectious diseases - 9 May 2014
Chabierski Stefan, Barzon Luisa, Papa Anna, Niedrig Matthias, Bramson Jonathan L, Richner Justin M, Palù Giorgio, Diamond Michael S, Ulbert Sebastian
Abstract excerpt
BACKGROUND: West Nile Virus (WNV) is an emerging mosquito-transmitted flavivirus that continues to spread and cause disease throughout several parts of the world, including Europe and the Americas. Specific diagnosis of WNV infections using current serological testing is complicated by the high degree of cross-reactivity between antibodies against other clinically relevant flaviviruses, including dengue,...
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