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Specific detection of dengue and Zika virus antibodies using envelope proteins with mutations in the conserved fusion loop

1 Jan 2017

Abstract excerpt

Detection of antibodies is widely used for the diagnosis of infections with arthropod-borne flaviviruses including dengue (DENV) and Zika virus (ZIKV). Due to the emergence of ZIKV in areas endemic for DENV, massive co-circulation is observed and methods to specifically diagnose these infections and differentiate them from each other are mandatory. However, serological assays for flaviviruses in general, and for...

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PMID: 29116222
DOI: 10.1038/emi.2017.87

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