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Protective Efficacy of a Chimeric Insect-Specific Flavivirus Vaccine against West Nile Virus

29 May 2020

Abstract excerpt

Virulent strains of West Nile virus (WNV) are highly neuro-invasive and human infection is potentially lethal. However, no vaccine is currently available for human use. Here, we report the immunogenicity and protective efficacy of a vaccine derived from a chimeric virus, which was constructed using the structural proteins (prM and E) of the Kunjin strain of WNV (WNVKUN) and the genome backbone of the...

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Share to Insect symbiosis and bacterial influences
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PMID: 32485930
DOI: 10.3390/vaccines8020258

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