Article
Pathway-driven discovery of rare mutational impact on cancer.
BioMed research international - 1 Jan 2014
Ahn TaeJin, Park Taesung
Abstract excerpt
Identifying driver mutation is important in understanding disease mechanism and future application of custom tailored therapeutic decision. Functional analysis of mutational impact usually focuses on the gene expression level of the mutated gene itself. However, complex regulatory network may cau...
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