Article
Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism - 1 Aug 2014
Kobaly Kristen, Vellanki Priyathama, Sisk Ryan K, Armstrong Loren, Lee Ji Young, Lee Jungwha, Hayes M Geoffrey, Urbanek Margrit, Legro Richard S, Dunaif Andrea
Abstract excerpt
CONTEXT: Polycystic ovary syndrome (PCOS) is a highly heritable complex trait. Parents of affected women have reproductive and metabolic phenotypes. OBJECTIVE: We tested the hypothesis that there are parental effects on the heritability of fasting dysglycemia in women with PCOS. DESIGN AND SETTING: This was a cross-sectional study at an academic medical center. PARTICIPANTS: PARTICIPANTS included 367 women with...
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