Article
TAF7L modulates brown adipose tissue formation.
eLife - 29 May 2014
Zhou Haiying, Wan Bo, Grubisic Ivan, Kaplan Tommy, Tjian Robert
Abstract excerpt
Brown adipose tissue (BAT) plays an essential role in metabolic homeostasis by dissipating energy via thermogenesis through uncoupling protein 1 (UCP1). Previously, we reported that the TATA-binding protein associated factor 7L (TAF7L) is an important regulator of white adipose tissue (WAT) differentiation. In this study, we show that TAF7L also serves as a molecular switch between brown fat and muscle lineages...
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