Article
Regulation of the unbalanced redox state in a Schizosaccharomyces pombe tert-butyl hydroperoxide-resistant mutant.
Acta biologica Hungarica - 1 Jun 2014
Gazdag Z, Kálmán Nikoletta, Blaskó Agnes, Virág Eszter, Belágyi J, Pesti M
Abstract excerpt
The one-gene mutation in the tert-butyl hydroperoxide-resistant mutant hyd1-190 of the fission yeast Schizosaccharomyces pombe led to a 4-fold increase in resistance to t-BuOOH and decreased specific concentrations of superoxide and total thiols in comparison with the parental strain hyd+. It suggested an unbalanced redox state of the cells, which induced continuously increased specific activities of glutathione...
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