Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.

BioMed research international - 1 Jan 2014

Stancheva Gergana, Goranova Teodora, Laleva Maria, Kamenova Margarita, Mitkova Atanaska, Velinov Nikolay, Poptodorov George, Mitev Vanio, Kaneva Radka, Gabrovsky Nikolay

Abstract excerpt

Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact on overall survival 106 glioblastoma patients were analysed. IDH1 mutations were detected in 13 and IDH2 mutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bulgaria
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Isocitrate Dehydrogenase

Share to Kaplan-Meier Estimate

Share to Loss of Heterozygosity

Share to Multivariate Analysis

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 24868540
DOI: 10.1155/2014/654727
PMCID: PMC4017788

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IDH1/IDH2 but not TP53 mutations predict prognosis in Bulgarian glioblastoma patients.PMID 24868540Read ↗

Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.Semantic proximity Read ↗

[Isocitrate dehydrogenase type I mutation as a prognostic factor in glioblastoma and a literature review].Semantic proximity Read ↗

Association of TP53 Alteration with Tissue Specificity and Patient Outcome of IDH1-Mutant Glioma.Semantic proximity Read ↗

IDH1 mutation is associated with improved overall survival in patients with glioblastoma: a meta-analysis.Semantic proximity Read ↗

Genetic alterations of IDH1 and Vegf in brain tumors.Semantic proximity Read ↗

Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients.Semantic proximity Read ↗

EGFR Amplification and IDH Mutations in Glioblastoma Patients of the Northeast of Morocco.Semantic proximity Read ↗

IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme.Semantic proximity Read ↗

Prevalence of IDH1/2 Mutations in Different Subtypes of Glioma in the North-East Population of Morocco.Semantic proximity Read ↗

Clinical prognostic value of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in glioblastoma.Semantic proximity Read ↗

Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors.Semantic proximity Read ↗

IDH-Mutation Is a Weak Predictor of Long-Term Survival in Glioblastoma Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.