Article
Association of single nucleotide polymorphisms of ERCC1 and XPF with colorectal cancer risk and interaction with tobacco use.
Gene - 10 Sept 2014
Hou Ruizhi, Liu Yan, Feng Ye, Sun Libo, Shu Zhenbo, Zhao Jisheng, Yang Shujuan
Abstract excerpt
We investigated the association between polymorphisms in excision repair cross-complementation group 1 (ERCC1) (rs3212986, rs2298881 and rs11615) and xeroderma pigmentosum-complementation group F (XPF) (rs2276466 and rs6498486) and risk of colorectal cancer. A 1:1 matched case-control study was conducted. Conditional regression analysis indicated that individuals carrying the ERCC1 TT genotype and T...
