Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SCUBE3 (signal peptide-CUB-EGF domain-containing protein 3) modulates fibroblast growth factor signaling during fast muscle development.

The Journal of biological chemistry - 4 Jul 2014

Tu Cheng-Fen, Tsao Ku-Chi, Lee Shyh-Jye, Yang Ruey-Bing

Abstract excerpt

SCUBE3 (signal peptide CUB-EGF-like domain-containing protein 3) belongs to a newly identified secreted and cell membrane-associated SCUBE family, which is evolutionarily conserved in vertebrates. Scube3 is predominantly expressed in a variety of developing tissues in mice such as somites, neural tubes, and limb buds. However, its function during development remains unclear. In this study, we first showed that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium-Binding Proteins
Share to Fibroblast Growth Factor 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Muscle Development

Share to MyoD Protein

Share to Oligonucleotides, Antisense

Share to Receptor, Fibroblast Growth Factor, Type 4

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24849601
DOI: 10.1074/jbc.M114.551929
PMCID: PMC4081933

Genes

SCUBE3
EGF
FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SCUBE3 (signal peptide-CUB-EGF domain-containing protein 3) modulates fibroblast growth factor signaling during fast muscle development.PMID 24849601Read ↗

Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterningSemantic proximity Read ↗

Scube2 mediates Hedgehog signalling in the zebrafish embryo.Semantic proximity Read ↗

Muscular dystrophy begins early in embryonic development deriving from stem cell loss and disrupted skeletal muscle formation.Semantic proximity Read ↗

Scube activity is necessary for Hedgehog signal transduction in vivo.Semantic proximity Read ↗

The embryonic muscle transcriptome of Caenorhabditis elegansSemantic proximity Read ↗

COPS3 AS lncRNA enhances myogenic differentiation and maintains fast-type myotube phenotype.Semantic proximity Read ↗

Stac3 is a novel regulator of skeletal muscle development in mice.Semantic proximity Read ↗

Expression of LIM domain-binding 3 (LDB3), a striated muscle Z-band alternatively spliced PDZ-motif protein in the nervous systemSemantic proximity Read ↗

The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.Semantic proximity Read ↗

Characterization of a mouse Scube3 reporter line.Semantic proximity Read ↗

Expression of striated muscle Z-band alternatively spliced PDZ-motif protein LIM domain-binding 3 in the nervous systemSemantic proximity Read ↗

Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.