Article
The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.
G3 (Bethesda, Md.) - 7 Dec 2016
Fuchs Helmut, Sabrautzki Sibylle, Przemeck Gerhard K H, Leuchtenberger Stefanie, Lorenz-Depiereux Bettina, Becker Lore, Rathkolb Birgit, Horsch Marion, Garrett Lillian, Östereicher Manuela A, Hans Wolfgang, Abe Koichiro, Sagawa Nobuho, Rozman Jan, Vargas-Panesso Ingrid L, Sandholzer Michael, Lisse Thomas S, Adler Thure, Aguilar-Pimentel Juan Antonio, Calzada-Wack Julia, Ehrhard Nicole, Elvert Ralf, Gau Christine, Hölter Sabine M, Micklich Katja, Moreth Kristin, Prehn Cornelia, Puk Oliver, Racz Ildiko, Stoeger Claudia, Vernaleken Alexandra, Michel Dian, Diener Susanne, Wieland Thomas, Adamski Jerzy, Bekeredjian Raffi, Busch Dirk H, Favor John, Graw Jochen, Klingenspor Martin, Lengger Christoph, Maier Holger, Neff Frauke, Ollert Markus, Stoeger Tobias, Yildirim Ali Önder, Strom Tim M, Zimmer Andreas, Wolf Eckhard, Wurst Wolfgang, Klopstock Thomas, Beckers Johannes, Gailus-Durner Valerie, Hrabé de Angelis Martin
Abstract excerpt
The vertebrate Scube (Signal peptide, CUB, and EGF-like domain-containing protein) family consists of three independent members, Scube1-3, which encode secreted cell surface-associated membrane glycoproteins. Limited information about the general function of this gene family is available, and their roles during adulthood. Here, we present the first Scube3 mutant mouse line (Scube3N294K/N294K), which clearly shows...
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