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Article

Mechanisms of transcriptional activation of the mouse claudin-5 promoter by estrogen receptor alpha and beta.

Molecular and cellular endocrinology - 5 Jul 2014

Burek Malgorzata, Steinberg Katrin, Förster Carola Y

Abstract excerpt

Claudin-5 is an integral membrane protein and a critical component of endothelial tight junctions that control paracellular permeability. Claudin-5 is expressed at high levels in the brain vascular endothelium. Estrogens have multiple effects on vascular physiology and function. The biological actions of estrogens are mediated by two different estrogen receptor (ER) subtypes, ER alpha and ER beta. Estrogens have...

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PMID: 24846172
DOI: 10.1016/j.mce.2014.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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