Article
Frequency of SPINK1 N34S mutation in acute and recurrent acute pancreatitis.
Journal of hepato-biliary-pancreatic sciences - 1 Sept 2014
Rai Praveer, Sharma Anjali, Gupta Ankur, Aggarwal Rakesh
Abstract excerpt
BACKGROUND: Several studies have reported association of c.101A>G (p.N34S) mutation in SPINK1 gene with chronic pancreatitis; however, the data on its relationship with acute pancreatitis (AP) and recurrent acute pancreatitis (RAP) are limited. METHODS: We studied 183 unrelated patients with AP and RAP and 168 healthy controls for p.N34S variant in SPINK1 gene using sequencing of genomic DNA. RESULTS: SPINK1...
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