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Article

Oncogenic mutations in melanomas and benign melanocytic nevi of the female genital tract.

Journal of the American Academy of Dermatology - 1 Aug 2014

Tseng Diane, Kim Julie, Warrick Andrea, Nelson Dylan, Pukay Marina, Beadling Carol, Heinrich Michael, Selim Maria Angelica, Corless Christopher L, Nelson Kelly

Abstract excerpt

BACKGROUND: The genetic heterogeneity of melanomas and melanocytic nevi of the female genital tract is poorly understood. OBJECTIVE: We aim to characterize the frequency of mutations of the following genes: BRAF, NRAS, KIT, GNA11, and GNAQ in female genital tract melanomas. We also characterize the frequency of BRAF mutations in female genital tract melanomas compared with melanocytic nevi. METHODS: Mutational...

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Topics

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Share to DNA, Neoplasm
Share to Genital Neoplasms, Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits

Share to GTP-Binding Protein alpha Subunits, Gq-G11

Share to GTP Phosphohydrolases

Share to Melanoma

Share to Nevus, Pigmented

Share to Proto-Oncogene Proteins c-kit

Source

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Identifiers

PMID: 24842760
DOI: 10.1016/j.jaad.2014.03.033
PMCID: PMC4450888

Genes

BRAF
KIT
NRAS
GNA11
GNAQ

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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