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Article

Female genitourinary tract melanoma: mutation analysis with clinicopathologic correlation: a single-institution experience.

Melanoma research - 1 Dec 2018

Saglam Ozlen, Naqvi Syeda M H, Zhang Yonghong, Mesa Tania, Teer Jamie K, Yoder Sean, Lee Jae, Messina Jane

Abstract excerpt

Female genitourinary tract melanoma (FGTM) is a rare and often-fatal form of mucosal melanoma. We describe our institutional experience with 55 cases of FGTM, 16 of which were evaluated with next-generation sequencing targeting 151 cancer-associated genes. Tumors tended to be thicker than conventional melanoma at presentation (median: 3.2 mm), were frequently ulcerated (50%), and characterized by incomplete...

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Identifiers

PMID: 30028779
DOI: 10.1097/CMR.0000000000000480
PMCID: PMC6205913

Genes

ATRX
BRAF
KIT
NRAS

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