Article
Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT.
PloS one - 1 Jan 2014
Bochem Andrea E, Holleboom Adriaan G, Romijn Johannes A, Hoekstra Menno, Dallinga Geesje M, Motazacker Mahdi M, Hovingh G Kees, Kuivenhoven Jan A, Stroes Erik S G
Abstract excerpt
INTRODUCTION: Adrenal steroidogenesis is essential for human survival and depends on the availability of the precursor cholesterol. Male subjects with low plasma levels of high density lipoprotein (HDL) cholesterol are characterized by decreased adrenal function. Whether this is also the case in female subjects with low plasma HDL-C levels is unresolved to date. FINDINGS: 15 female ATP binding cassette...
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