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Article

Associations of genetic polymorphisms of Siglecs with human diseases.

Glycobiology - 1 Sept 2014

Angata Takashi

Abstract excerpt

Genetic polymorphism studies in humans provide unique opportunities to understand human biology and the mechanisms of diseases. Correlations between polymorphisms in the genes encoding human Siglecs and various diseases have been reported. Leading examples, such as the CD33 polymorphism associated with late-onset Alzheimer's disease, are well supported by genetic replication and mechanistic studies, while some...

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Source

Identifiers

PMID: 24841380
DOI: 10.1093/glycob/cwu043

Genes

MAG
SIGLEC14
SIGLEC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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