Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genome-wide association meta-analysis of preschool internalizing problems.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jun 2014

Benke Kelly S, Nivard Michel G, Velders Fleur P, Walters Raymond K, Pappa Irene, Scheet Paul A, Xiao Xiangjun, Ehli Erik A, Palmer Lyle J, Whitehouse Andrew J O, Verhulst Frank C, Jaddoe Vincent W, Rivadeneira Fernando, Groen-Blokhuis Maria M, van Beijsterveldt Catharina E M, Davies Gareth E, Hudziak James J, Lubke Gitta H, Boomsma Dorret I, Pennell Craig E, Tiemeier Henning, Middeldorp Christel M

Abstract excerpt

OBJECTIVE: Preschool internalizing problems (INT) are highly heritable and moderately genetically stable from childhood into adulthood. Gene-finding studies are scarce. In this study, the influence of genome-wide measured single nucleotide polymorphisms (SNPs) was investigated in 3 cohorts (total N = 4,596 children) in which INT was assessed with the same instrument, the Child Behavior Checklist (CBCL). METHOD:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child Behavior Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Cohort Studies

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Share to Registries

Source

Identifiers

PMID: 24839885
DOI: 10.1016/j.jaac.2013.12.028

Genes

PCSK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genome-wide association meta-analysis of preschool internalizing problems.PMID 24839885Read ↗

Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms.Semantic proximity Read ↗

Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis.Semantic proximity Read ↗

Examining Differences in the Genetic and Functional Architecture of ADHD Diagnosed in Childhood and AdulthoodSemantic proximity Read ↗

Single Nucleotide Polymorphism Heritability of a General Psychopathology Factor in Children.Semantic proximity Read ↗

The effects of the interplay of genetics and early environmental risk on the course of internalizing symptoms from late childhood through adolescence.Semantic proximity Read ↗

The development of childhood internalising problems: A meta-analysis of epigenome-wide-association-studiesSemantic proximity Read ↗

Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders.Semantic proximity Read ↗

A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology SpectraSemantic proximity Read ↗

Integrating HiTOP and RDoC frameworks Part I: Genetic architecture of externalizing and internalizing psychopathology.Semantic proximity Read ↗

The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology.Semantic proximity Read ↗

Integrating HiTOP and RDoC Frameworks Part I: Genetic Architecture of Externalizing and Internalizing PsychopathologySemantic proximity Read ↗

Maternal and paternal effects on offspring internalizing problems: Results from genetic and family-based analyses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.