Article
An insertion-deletion polymorphism in interleukin-1α gene associated with susceptibility to preeclampsia.
Hypertension in pregnancy - 1 Nov 2014
Chen Peng, Zhou Bin, Zhang Kui, Zhang Zhu, Song Yaping, Pu Yan, Yang Yan, Zhang Yanyan, Zhou Rong, Wang Tao, Zhang Lin
Abstract excerpt
OBJECTIVE: To determine whether preeclampsia is associated with polymorphisms in the IL-1α. METHODS: We genotyped a Chinese population (212 women with preeclampsia and 203 controls) for the polymorphism of the interleukin-1α gene (3'-untranslated region). Clinical data were collected from medical records. RESULTS: Significantly reduced preeclampsia risk was found to be associated with both I allele (p < 0.001,...
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