Molecular genetics and endometrial cancer.

Abstract excerpt

Endometrial cancer is the ninth most common malignancy in females. Inherited forms of this malignancy exist. Mutations in mismatch repair genes result in hereditary non-polyposis colorectal cancer, which confers a lifetime risk of bowel cancer between 60-80% and an endometrial cancer risk of up to 60%. Current screening involves the use of transvaginal ultrasound and hysteroscopy. Genetic testing for mutations in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Colorectal Neoplasms, Hereditary Nonpolyposis
• Share to Endometrial Neoplasms
• Share to Genes, erbB-2