Article
Advances in the molecular genetics of endometrial cancer (Review).
Oncology reports - 1 Jan 2000
Esteller M, Xercavins J, Reventos J
Abstract excerpt
Recent studies have identified some of the genetic alterations involved in endometrial carcinoma development. Transforming genes, including K-ras and c-erbB2/neu oncogenes and the p53, PTEN and hMLH1 tumor suppressor genes, are the most frequently altered. In addition, endometrial carcinomas express high levels of chemoresistance markers, including the MDR-1 or the MRP genes. The genetic background of an...
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