Article
Correlation of interleukin-10 gene haplotype with hepatocellular carcinoma in Taiwan.
Tissue antigens - 1 Feb 2006
Tseng L-H, Lin M-T, Shau W-Y, Lin W-C, Chang F-Y, Chien K-L, Hansen J A, Chen D-S, Chen P-J
Abstract excerpt
Polymorphisms in cytokine genes can influence immune responses, inflammation and tissue injury, and may affect the outcome of hepatitis B virus (HBV) infection. We analyzed single nucleotide polymorphisms (SNP) in the interleukin (IL)-10 gene among 344 HBV carriers and 208 patients with hepatocellular carcinoma (HCC). Genotypes and haplotypes were tested for association with HCC. IL-10/-592 C/C genotype was...
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