Article
[Genetic predispositions in drug allergy: the role of HLA].
Revue medicale suisse - 16 Apr 2014
Bergmann M M, Villard J, Caubet J-C
Abstract excerpt
The pathophysiology of drug allergy is complex and relies on the interaction between the drug and the immune system in combination with environmental factors, in particular viruses. Genetic predisposition plays an important role in drug allergy. Recent publications have shown the importance of HLA genes, particularly in the delayed hypersensitivity reactions. In fact, particular HLA alleles were identified as...
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