Article
Downregulated miR-31 level associates with poor prognosis of gastric cancer and its restoration suppresses tumor cell malignant phenotypes by inhibiting E2F2.
Oncotarget - 14 Jun 2016
Wang Huaidong, Zhang Xiaotian, Liu Yuxin, Ni Zhaohui, Lin Yan, Duan Zipeng, Shi Yue, Wang Guoqing, Li Fan
Abstract excerpt
The miRNA microarray analysis showed that miR-31 was reduced in gastric cancer. This study further assessed miR-31 expression and role of miR-31 in gastric cancer tissues and cell lines. The data showed that miR-31 expression was down-regulated in 40 cases of gastric cancer tissues compared to the adjacent normal tissues, and low expression of miR-31 was associated with poor tumor differentiation, lymph node...
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