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Article

Chemokine receptor CCR6 expression is regulated by miR-518a-5p in colorectal cancer cells.

Journal of translational medicine - 21 Feb 2014

Rubie Claudia, Kruse Bianca, Frick Vilma Oliveira, Kölsch Kathrin, Ghadjar Pirus, Wagner Mathias, Grässer Friedrich, Wagenpfeil Stefan, Glanemann Mathias

Abstract excerpt

BACKGROUND: Recently, involvement of the chemokine/receptor system CCL20/CCR6 in colorectal cancer (CRC) progression was shown. Here, we analyzed the functional interaction of miRNA-518-5p (miR-518a-5p) with CCR6 and its impact on CCR6 expression in CRC cells. METHODS: MiR-518a-5p was identified by computer software to potentially interact with CCR6. Hence, functional implications of miR-518a-5p with the 3'UTR of...

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Identifiers

PMID: 24559209
DOI: 10.1186/1479-5876-12-48
PMCID: PMC3996063

Genes

CCR6
CCL20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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