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Article

Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells.

PloS one - 1 Jan 2014

Tai Tzong-Shyuan, Pai Sung-Yun, Ho I-Cheng

Abstract excerpt

The integral membrane protein 2a (Itm2a) is one of the BRICHOS domain-containing proteins and is structurally related to Itm2b and Itm2c. It is expressed preferentially in the T lineage among hematopoietic cells and is induced by MHC-mediated positive selection. However, its transcriptional regulation and function are poorly understood. Here we showed Itm2a to be a target gene of GATA-3, a T cell-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24831988
DOI: 10.1371/journal.pone.0096535
PMCID: PMC4022677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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