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Article

Expansion and somatic hypermutation of B-cell clones in rejected human kidney grafts.

Transplantation - 15 Oct 2014

Ferdman Jack, Porcheray Fabrice, Gao Baoshan, Moore Carolina, DeVito Julie, Dougherty Sarah, Thomas Margaret V, Farkash Evan A, Elias Nahel, Kawai Tatsuo, Malek Sayeed K, Tullius Stefan G, Wong Waichi, Zorn Emmanuel

Abstract excerpt

BACKGROUND: B-cell infiltrates are common in rejected kidney allografts, yet their composition is still unclear. The aim of our study was to characterize the clonal composition of B-cell infiltrates of rejected human kidney grafts. METHODS: We used a molecular approach to characterize the partial B-cell repertoires of 5 failed human kidney grafts with detectable B-cell infiltrates. A comparison between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24825521
DOI: 10.1097/TP.0000000000000124
PMCID: PMC4188704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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