Article
Activation of Bax in three models of retinitis pigmentosa.
Investigative ophthalmology & visual science - 13 May 2014
Comitato Antonella, Sanges Daniela, Rossi Alessandra, Humphries Marian M, Marigo Valeria
Abstract excerpt
PURPOSE: The process of photoreceptor cell death in retinitis pigmentosa is still not well characterized, and identification of common mechanisms will be instrumental for development of therapeutic strategies. Here we investigated activation of Bax in rd1, P23H transgenic, and Rho knockout retinas. METHODS: Bax activation was evaluated by immunofluorescence using anti-activated Bax-specific antibodies and by...
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