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Article

Association between restless legs syndrome and CLOCK and NPAS2 gene polymorphisms in schizophrenia.

Chronobiology international - 1 Aug 2014

Jung Jin-Sook, Lee Heon-Jeong, Cho Chul-Hyun, Kang Seung-Gul, Yoon Ho-Kyoung, Park Young-Min, Moon Joung-Ho, Yang Hee-Jung, Song Hyun-Mi, Kim Leen

Abstract excerpt

Previous studies have suggested that there is a genetic basis to restless legs syndrome (RLS) development. Occurrence of antipsychotic-induced RLS could also be due to differences in genetic susceptibility. We investigated whether CLOCK and NPAS2 gene polymorphisms are associated with RLS in schizophrenic patients on antipsychotics because RLS symptoms usually manifest during the evening and night. We assessed...

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Identifiers

PMID: 24824748
DOI: 10.3109/07420528.2014.914034

Genes

CLOCK
NPAS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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