Article
Lack of association of the rs1344706 ZNF804A variant with cognitive functions and DTI indices of white matter microstructure in two independent healthy populations.
Psychiatry research - 30 Apr 2014
Fernandes Carla Patricia Duarte, Westlye Lars Tjelta, Giddaluru Sudheer, Christoforou Andrea, Kauppi Karolina, Adolfsson Rolf, Nilsson Lars-Göran, Nyberg Lars, Lundervold Astri Johansen, Reinvang Ivar, Steen Vidar Martin, Le Hellard Stéphanie, Espeseth Thomas
Abstract excerpt
The rs1344706 single nucleotide polymorphism within intron 2 of the ZNF804A gene is strongly associated with schizophrenia and bipolar disorder. This variant has also been associated in some studies with a range of cognitive and neuroimaging phenotypes, but several studies have reported no effect on the same phenotypes in other samples. Here, we genotyped 670 healthy adult Norwegian subjects and 1753 healthy...
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