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Article

Loss-of-function of β-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans.

Scientific reports - 13 May 2014

van der Bent M Leontien, Sterken Mark G, Volkers Rita J M, Riksen Joost A G, Schmid Tobias, Hajnal Alex, Kammenga Jan E, Snoek L Basten

Abstract excerpt

C. elegans is extensively used to study the Wnt-pathway and most of the core-signalling components are known. Four β-catenins are important gene expression regulators in Wnt-signalling. One of these, bar-1, is part of the canonical Wnt-pathway. Together with Wnt effector pop-1, bar-1 forms a tran...

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Identifiers

PMID: 24819947
DOI: 10.1038/srep04926
PMCID: PMC4019968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24819947-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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