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Article

Effect of CYP2C19 polymorphisms on stiripentol administration in Japanese cases of Dravet syndrome.

Brain & development - 1 Feb 2015

Kouga Takeshi, Shimbo Hiroko, Iai Mizue, Yamashita Sumimasa, Ishii Atsushi, Ihara Yukiko, Hirose Shinichi, Yamakawa Kazuhiro, Osaka Hitoshi

Abstract excerpt

OBJECTIVE: The objective of this study was to investigate stiripentol (STP) administration in cases of Dravet syndrome (DS) by comparing CYP2C19 allelic polymorphisms with the clinical effects of STP, including plasma concentrations of concomitant drugs and adverse effects of STP. MATERIALS AND METHODS: Eleven cases of DS cases were included. Demographic and clinical characteristics of the cases (age at the study...

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Identifiers

PMID: 24819914
DOI: 10.1016/j.braindev.2014.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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