Article
Epidermal growth factor receptor (EGFR) pathway genes and interstitial lung disease: an association study.
Scientific reports - 13 May 2014
Li Chong, Wei Rongrong, Jones-Hall Yava L, Vittal Ragini, Zhang Min, Liu Wanqing
Abstract excerpt
The etiology and pathogenesis of idiopathic interstitial lung disease (ILD) remain incompletely understood. Genetic susceptibility to ILD has been demonstrated in previous studies. It is well known that EGFR inhibitors can induce ILD in human lung cancer patient with ethnic differences, which prompted us to hypothesize that genetic variation in EGFR pathway genes confer susceptibility to ILD. We aimed in this...
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