Article
Preexisting interstitial lung disease is inversely correlated to tumor epidermal growth factor receptor mutation in patients with lung adenocarcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 May 2013
Fujimoto Daichi, Tomii Keisuke, Otoshi Takehiro, Kawamura Takahisa, Tamai Koji, Takeshita Junpei, Tanaka Kosuke, Matsumoto Takeshi, Monden Kazuya, Nagata Kazuma, Otsuka Kyoko, Nakagawa Atsushi, Hata Akito, Tachikawa Ryo, Otsuka Kojiro, Hamakawa Hiroshi, Katakami Nobuyuki, Takahashi Yutaka, Imai Yukihiro
Abstract excerpt
INTRODUCTION: Interstitial lung disease (ILD), especially idiopathic pulmonary fibrosis, has been shown to be associated with lung carcinogenesis. However, an association between epidermal growth factor receptor (EGFR) mutation status and preexisting ILD in patients with lung adenocarcinoma is unknown. METHODS: Between January 2008 and April 2012, we analyzed 602 patients with lung adenocarcinoma. EGFR mutation...
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